[Tyr8]-Substance P, Neurokinin 1 tachykinin receptor agonist (ab142547)

Overview

  • Product name

    [Tyr8]-Substance P, Neurokinin 1 tachykinin receptor agonist
  • Description

    Neurokinin 1 tachykinin receptor agonist
  • Biological description

    Neurokinin 1 (NK1) tachykinin receptor agonist. Neurotransmitter effects. Involved in pain signal transmission, salivary gland secretion and neurogenic inflammation. Active in vitro and in vivo.
  • Purity

    > 95%
  • CAS Number

    55614-10-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Patel AB  et al. Replacement of phe(8) in substance P by tyr (Tyr(8)-SP) alters the conformation of the peptide in DMSO, water, and lipid bilayers. Biopolymers 50:602-12 (1999). Read more (PubMed: 10508963) »
  • Garces YI  et al. Lack of potent antinociceptive activity by substance P antagonist CP-96,345 in the rat spinal cord. Life Sci 52:353-60 (1993). Read more (PubMed: 7678436) »
  • McKee KT  et al. Identification of both NK1 and NK2 receptors in guinea-pig airways. Br J Pharmacol 110:693-700 (1993). Read more (PubMed: 7694756) »

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