Description

Associated products

Specifications

Our Abpromise guarantee covers the use of ab218119 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-TYRO3 antibody [EPR4308] (ab109231)

  • Form

    Lyophilised
  • Additional notes

    Reconstitution instructions:

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.

    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.

    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.

    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.

    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

General Info

  • Alternative names

    • Brt
    • BYK
    • DTK
    • Etk-2
    • protein tyrosine kinase 3
    • Rek
    • RSE
    • SKY
    • Tif
    • tyro3
    • TYRO3 protein tyrosine kinase
    • TYRO3_HUMAN
    • Tyrosine-protein kinase byk
    • Tyrosine-protein kinase DTK
    • Tyrosine-protein kinase receptor TYRO3
    • Tyrosine-protein kinase RSE
    • Tyrosine-protein kinase SKY
    • Tyrosine-protein kinase TIF
    see all
  • Function

    May be involved in cell adhesion processes, particularly in the central nervous system. In case of filovirus infection, seems to function as a cell entry factor.
  • Tissue specificity

    Abundant in the brain and lower levels in other tissues.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt

References

ab218119 has not yet been referenced specifically in any publications.

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