Key features and details
- Rabbit polyclonal to Tyrosyl tRNA synthetase/TyrRS
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Tyrosyl tRNA synthetase/TyrRS antibody
See all Tyrosyl tRNA synthetase/TyrRS primary antibodies
DescriptionRabbit polyclonal to Tyrosyl tRNA synthetase/TyrRS
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant fragment corresponding to Human Tyrosyl tRNA synthetase/TyrRS aa 307-528.
- 293T, A431, H1299, HeLaS3, MOLT4, Raji whole cell lysates; A431 cells
General notesKeep as a concentrated solution.
Previously labelled as Tyrosyl tRNA synthetase
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab155504 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 59 kDa.|
|ICC/IF||1/100 - 1/1000.|
FunctionCatalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Involvement in diseaseDefects in YARS are the cause of Charcot-Marie-Tooth disease dominant intermediate type C (CMTDIC) [MIM:608323]. CMTDIC is a form of Charcot-Marie-Tooth disease characterized by clinical and pathologic features intermediate between demyelinating and axonal peripheral neuropathies, and motor median nerve conduction velocities ranging from 25 to 45 m/sec.
Sequence similaritiesBelongs to the class-I aminoacyl-tRNA synthetase family.
Contains 1 tRNA-binding domain.
- Information by UniProt
- CMTDIC antibody
- SYYC_HUMAN antibody
- Tyrosine tRNA ligase, cytoplasmic antibody
Anti-Tyrosyl tRNA synthetase/TyrRS antibody (ab155504) at 1/1000 dilution + H1299 whole cell lysate at 30 µg
Predicted band size: 59 kDa
7.5% SDS PAGE
Immunofluorescent analysis of methanol-fixed A431 cells labeling Tyrosyl tRNA synthetase / TyrRS with ab155504 at 1/200 dilution. Lower panel co-stained with Hoechst 33342.
ab155504 has not yet been referenced specifically in any publications.