Overview

  • Product name

    Tyrphostin 47, EGFR tyrosine kinase inhibitor
  • Description

    EGFR tyrosine kinase inhibitor
  • Biological description

    Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (IC50 = 2.4 μM). Also inhibits platelet-derived growth factor (PDGF) receptor tyrosine kinase.
  • Purity

    > 99%
  • CAS Number

    122520-86-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Dvir A  et al. The inhibition of EGF-dependent proliferation of keratinocytes by tyrphostin tyrosine kinase blockers. J Cell Biol 113:857-65 (1991). Read more (PubMed: 1709168) »
  • Gazit A  et al. Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors. J Med Chem 32:2344-52 (1989). Read more (PubMed: 2552117) »
  • Yaish P  et al. Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors. Science 242:933-5 (1988). Read more (PubMed: 3263702) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141558.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up