Key features and details
- Potent, selective p210 tyrosine kinase inhibitor
- CAS Number: 140674-76-6
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameTyrphostin AG 957, p210 tyrosine kinase inhibitor
DescriptionPotent, selective p210 tyrosine kinase inhibitor
Potent, selective p210 tyrosine kinase inhibitor (IC50 values are 1 and 7.1 μM at p210bcr-abl and p140c-abl respectively). Able to induce apoptosis and growth arrest by affecting the phosphorylation state of PI3K/Akt.
Chemical name4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid methyl ester
Storage instructionsStore at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141172 has not yet been referenced specifically in any publications.