Product nameTZFP peptide
See all TZFP proteins and peptides
Amino Acid Sequence
Amino acids474 to 487
Our Abpromise guarantee covers the use of ab45517 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-TZFP antibody (ab26066)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- FANCC interacting protein
- FANCC-interacting protein
- Fanconi anemia zinc finger protein
FunctionDNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells.
Tissue specificityPredominantly expressed in testis. Some isoforms are ubiquitously expressed.
Sequence similaritiesBelongs to the krueppel C2H2-type zinc-finger protein family.
Contains 1 BTB (POZ) domain.
Contains 3 C2H2-type zinc fingers.
DomainThe C-terminal zinc finger domain functions as a transcriptional transactivator.
The BTB (POZ) domain possesses repressor activity.
Cellular localizationNucleus. Located in nuclear speckles.
- Information by UniProt
ab45517 has not yet been referenced specifically in any publications.