Key features and details
- Inhibitor of cholesterol synthesis and cellular transport
- CAS Number: 3039-71-2
- Soluble in DMSO to 50 mM and in water to 50 mM
- Form / State: Solid
- Source: Synthetic
Product nameU-18666A, cholesterol transport inhibitor
DescriptionInhibitor of cholesterol synthesis and cellular transport
Inhibitor of cholesterol synthesis and cellular transport. Impairs intracellular transport of LDL-derived cholesterol in CHO cells. Blocks the ability of LDL-derived cholesterol to suppress HMG-CoA reductase and LDL receptor activity. Weak inhibitor of Hedgehog signaling. Modulates APP cleavage in cultured cells. Tool compound for studying Niemann-Pick disease.
Chemical name(3β)-3-[2-(Diethylamino)ethoxy]-androst-5-en-17-one, hydrochloride
Storage instructionsShipped at Room Temperature. Store at Room Temperature. Store under desiccating conditions.
Solubility overviewSoluble in DMSO to 50 mM and in water to 50 mM
Refer to SDS for further information.
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab269882 has not yet been referenced specifically in any publications.