Overview

  • Product name

    U-83836E, Lazaroid antioxidant
  • Description

    Lazaroid antioxidant
  • Biological description

    Lazaroid antioxidant, a steroid compound that inhibits lipid peroxidation. Inhibits cell proliferation (IC50 = 6.30 mM). Potent free radical scavenger. Significantly protects against LPS induced lethality. Reduces secondary brain injury in a rabbit model of cryogenic trauma. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    122003-11-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Durmaz R  et al. Antiproliferative properties of the lazaroids U-83836E and U-74389G on glioma cells in vitro. Pathol Oncol Res 5:223-8 (1999). Read more (PubMed: 10491022) »
  • Altavilla D  et al. Inhibition of tumour necrosis factor and reversal of endotoxin-induced shock by U-83836E, a 'second generation' lazaroid in rats. Br J Pharmacol 124:1293-9 (1998). Read more (PubMed: 9720803) »
  • Wilson JT  et al. U83836E reduces secondary brain injury in a rabbit model of cryogenic trauma. J Trauma 39:473-7; discussion 477-9 (1995). Read more (PubMed: 7473911) »
See 1 Publication for this product

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