Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody (ab96333)
Key features and details
- Rabbit polyclonal to Ubiquinol-Cytochrome C Reductase Core Protein I
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody
See all Ubiquinol-Cytochrome C Reductase Core Protein I primary antibodies -
Description
Rabbit polyclonal to Ubiquinol-Cytochrome C Reductase Core Protein I -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat, Cow, Monkey -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-176 of Human Ubiquinol-Cytochrome C Reductase Core Protein I (NP_003356)
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Positive control
- HepG2 whole cell lysate (ab7900) and 293T cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96333 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 53 kDa.
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IHC-P |
1/100 - 1/1000.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 53 kDa. |
IHC-P
1/100 - 1/1000. |
Target
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Function
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. -
Sequence similarities
Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily. -
Cellular localization
Mitochondrion inner membrane. - Information by UniProt
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Database links
- Entrez Gene: 282393 Cow
- Entrez Gene: 7384 Human
- Entrez Gene: 22273 Mouse
- Entrez Gene: 301011 Rat
- Omim: 191328 Human
- SwissProt: P31800 Cow
- SwissProt: P31930 Human
- SwissProt: Q8K2S8 Mouse
see all -
Alternative names
- Complex III subunit 1 antibody
- Core protein I antibody
- Cytochrome b c1 complex subunit 1, mitochondrial antibody
see all
Images
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Anti-Ubiquinol-Cytochrome C Reductase Core Protein I antibody (ab96333) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 53 kDa
7.5% SDS PAGE -
Immunohistochemical analysis of PFA fixed, paraffin-embedded mouse liver tissue labeling Ubiquinol-Cytochrome C Reductase Core Protein 1 with ab96333 at 1/500 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab96333 has been referenced in 5 publications.
- Shan W et al. Critical role of UQCRC1 in embryo survival, brain ischemic tolerance and normal cognition in mice. Cell Mol Life Sci 76:1381-1396 (2019). PubMed: 30666338
- Alberdi P et al. The redox metabolic pathways function to limit Anaplasma phagocytophilum infection and multiplication while preserving fitness in tick vector cells. Sci Rep 9:13236 (2019). PubMed: 31520000
- Reyes A et al. RNase H1 Regulates Mitochondrial Transcription and Translation via the Degradation of 7S RNA. Front Genet 10:1393 (2019). PubMed: 32082360
- Peng X et al. Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-a-mediated signaling. Cell Death Dis 5:e1367 (2014). WB ; Human . PubMed: 25118927
- Chen X et al. Identification of differentially expressed proteins between bull X and Y spermatozoa. J Proteomics : (2012). WB . PubMed: 22820535