Product nameAnti-Ubiquitin thioesterase zranb1-B antibody
DescriptionRabbit polyclonal to Ubiquitin thioesterase zranb1-B
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Zebrafish
Recombinant fragment within Zebrafish Ubiquitin thioesterase zranb1-B aa 149-324. The exact sequence is proprietary.
Database link: A0JMQ9
- WB: Lysate/extracts of zebrafish embryos (24 hours post fertilization)
(Please refer to the vial label for the specific concentration)
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin
Constituents: PBS, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab209837 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 81 kDa.|
FunctionSpecifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. May play a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
Sequence similaritiesBelongs to the peptidase C64 family.
Contains 2 ANK repeats.
Contains 1 OTU domain.
Contains 3 RanBP2-type zinc fingers.
DomainThe OTU domain mediates the deubiquitinating activity.
The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- Ubiquitin thioesterase zranb1-B antibody
- Zinc finger Ran-binding domain-containing protein 1-B antibody
- zranb1b antibody
- ZRN1B_DANRE antibody
ab209837 has not yet been referenced specifically in any publications.