Anti-Ubiquitin thioesterase zranb1-B antibody (ab209837)

Overview

  • Product name

    Anti-Ubiquitin thioesterase zranb1-B antibody
  • Description

    Rabbit polyclonal to Ubiquitin thioesterase zranb1-B
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Zebrafish
  • Immunogen

    Recombinant fragment within Zebrafish Ubiquitin thioesterase zranb1-B aa 149-324. The exact sequence is proprietary.
    Database link: A0JMQ9

  • Positive control

    • WB: Lysate/extracts of zebrafish embryos (24 hours post fertilization)
  • General notes

    (Please refer to the vial label for the specific concentration)

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.025% Proclin
    Constituents: PBS, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab209837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 81 kDa.

Target

  • Function

    Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. May play a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
  • Sequence similarities

    Belongs to the peptidase C64 family.
    Contains 2 ANK repeats.
    Contains 1 OTU domain.
    Contains 3 RanBP2-type zinc fingers.
  • Domain

    The OTU domain mediates the deubiquitinating activity.
    The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

    • Alternative names

      • Ubiquitin thioesterase zranb1-B antibody
      • Zinc finger Ran-binding domain-containing protein 1-B antibody
      • zranb1b antibody
      • ZRN1B_DANRE antibody

    Images

    • Anti-Ubiquitin thioesterase zranb1-B antibody (ab209837) at 1/1000 dilution + Lysate/extract of zebrafish embryos (24 hours post fertilization)

      Predicted band size: 81 kDa



      7.5 % SDS-PAGE

    References

    ab209837 has not yet been referenced specifically in any publications.

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