• Product name

    Anti-UGGT/UGT1 antibody [EPR5105]
    See all UGGT/UGT1 primary antibodies
  • Description

    Rabbit monoclonal [EPR5105] to UGGT/UGT1
  • Host species

  • Tested applications

    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human UGGT/UGT1 aa 1500-1600.
    Database link: Q9NYU2

  • Positive control

    • Human skeletal muscle, BXPC-3, SH-SY5Y, and MCF7 lysates, Human brain tissue
  • General notes



     This product was previously labelled as UGGT


    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.


  • Form

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.05% Sodium azide
    Constituents: 0.1% BSA, 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

  • Clone number

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab124879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Detects a band of approximately 170 kDa (predicted molecular weight: 177 kDa).
IHC-P 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Function

      Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
    • Tissue specificity

      Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
    • Pathway

      Protein modification; protein glycosylation.
    • Sequence similarities

      Belongs to the glycosyltransferase 8 family.
    • Domain

      The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects.
    • Cellular localization

      Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
    • Information by UniProt
    • Database links

    • Alternative names

      • GT antibody
      • HUGT1 antibody
      • UDP glucose glycoprotein glucosyltransferase 1 antibody
      • UDP Glucose Glycoprotein Glucosyltransferase antibody
      • UDP--Glc:glycoprotein glucosyltransferase antibody
      • UDP-glucose ceramide glucosyltransferase-like 1 antibody
      • UDP-glucose:glycoprotein glucosyltransferase 1 antibody
      • UGCGL1 antibody
      • UGGG1 antibody
      • UGGG1_HUMAN antibody
      • UGGT antibody
      • Uggt1 antibody
      • UGT1 antibody
      • UGTR antibody
      see all


    • Staining of UGGT/UGT1 in Paraffin-embedded Human brain tissue by Immunohistochemistry using ab124879 at a dilution of 1/100.

    • All lanes : Anti-UGGT/UGT1 antibody [EPR5105] (ab124879) at 1/10000 dilution

      Lane 1 : Human skeletal muscle lysate
      Lane 2 : BXPC-3 cell lysate
      Lane 3 : SH-SY5Y cell lysate
      Lane 4 : MCF7 cell lysate

      Lysates/proteins at 10 µg per lane.

      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 177 kDa


    This product has been referenced in:

    • Ilca FT  et al. TAPBPR mediates peptide dissociation from MHC class I using a leucine lever. Elife 7:N/A (2018). Read more (PubMed: 30484775) »
    • Neerincx A  et al. TAPBPR bridges UDP-glucose:glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway. Elife 6:N/A (2017). Read more (PubMed: 28425917) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab124879.
    Please use the links above to contact us or submit feedback about this product.

    For licensing inquiries, please contact partnerships@abcam.com

    Sign up