Overview

  • Product name
    Anti-UGT1A1 antibody
    See all UGT1A1 primary antibodies
  • Description
    Rabbit polyclonal to UGT1A1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human UGT1A1 aa 1-200 (N terminal).
    Sequence:

    MAVESQGGRP LVLGLLLCVL GPVVSHAGKI LLIPVDGSHW LSMLGAIQQL QQRGHEIVVL APDASLYIRD GAFYTLKTYP VPFQREDVKE SFVSLGHNVF ENDSFLQRVI KTYKKIKKDS AMLLSGCSHL LHNKELMASL AESSFDVMLT DPFLPCSPIV AQYLSLPTVF FLHALPCSLE FEATQCPNPF SYVPRPLSSH


    Database link: P22309

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • HepG2, SGC996, SH-SY5Y, mouse lung, liver and kidney lysates; rat liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab194697 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 60 kDa.
IHC-P 1/50 - 1/200.

Target

  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • BILIQTL1 antibody
    • Bilirubin specific UDPGT isozyme 1 antibody
    • bilirubin UDP glucuronosyltransferase 1 1 antibody
    • bilirubin UDP glucuronosyltransferase isozyme 1 antibody
    • Bilirubin-specific UDPGT isozyme 1 antibody
    • EC 2.4.1.17 antibody
    • GNT1 antibody
    • HUG BR1 antibody
    • HUG-BR1 antibody
    • HUGBR1 antibody
    • PHENOL/BILIRUBIN UDP GLUCURONOSYLTRANSFERASE antibody
    • UD11_HUMAN antibody
    • UDP glucuronosyltransferase 1 1 [Precursor] antibody
    • UDP glucuronosyltransferase 1 family polypeptide A1 antibody
    • UDP glucuronosyltransferase 1A1 antibody
    • UDP GLYCOSYLTRANSFERASE 1 antibody
    • UDP-glucuronosyltransferase 1-1 antibody
    • UDP-glucuronosyltransferase 1-A antibody
    • UDP-glucuronosyltransferase 1A1 antibody
    • UDPGT antibody
    • UDPGT 1-1 antibody
    • UGT 1A antibody
    • UGT-1A antibody
    • UGT1 antibody
    • UGT1 01 antibody
    • UGT1*1 antibody
    • UGT1-01 antibody
    • UGT1.1 antibody
    • UGT1A antibody
    • Ugt1a1 antibody
    • URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE, BILIRUBIN/PHENOL antibody
    • URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1 antibody
    • URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1 antibody
    see all

Images

  • Western blot - Anti-UGT1A1 antibody (ab194697)
    Western blot - Anti-UGT1A1 antibody (ab194697)
    All lanes : Anti-UGT1A1 antibody (ab194697) at 1/500 dilution

    Lane 1 : HepG2 cell lysate
    Lane 2 : SGC996 cell lysate
    Lane 3 : SH-SY5Y cell lysate
    Lane 4 : mouse liver lysate
    Lane 5 : mouse kidney lysate
    Lane 6 : mouse lung lysate
    Lane 7 : rat liver lysate

    Predicted band size: 60 kDa

References

This product has been referenced in:
  • Guan HY  et al. Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity. Front Pharmacol 8:769 (2017). Read more (PubMed: 29163158) »
  • Wang H  et al. Glycyrrhizin and glycyrrhetinic acid inhibits alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption. Toxicology 386:133-142 (2017). WB ; Mouse . Read more (PubMed: 28549656) »

See all 3 Publications for this product

Publishing research using ab194697? Please let us know so that we can cite the reference in this datasheet.

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-UGT1A1 antibody

 Good
Abreviews
Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Rat Tissue sections (Ovary)
Antigen retrieval step
Enzymatic
Permeabilization
No
Specification
Ovary
Blocking step
Serum as blocking agent for 45 minute(s) · Concentration: 1.5%
Fixative
Formaldehyde
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Submitted Dec 02 2015

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