Overview

  • Product name
    Anti-UGT1A8 antibody [EPR11949]
  • Description
    Rabbit monoclonal [EPR11949] to UGT1A8
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
    Unsuitable for: Flow Cyt or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human UGT1A8 aa 500 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: Q9HAW9

  • Positive control
    • HT-29 and SW480 cell lysates; Human colon tissue; SW480 cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab172624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 60 kDa.
IHC-P 1/250 - 1/500.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt or IP.
  • Target

    • Function
      UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
    • Tissue specificity
      Colon specific.
    • Sequence similarities
      Belongs to the UDP-glycosyltransferase family.
    • Cellular localization
      Microsome. Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • UD18_HUMAN antibody
      • UDP glucuronosyltransferase 1 family polypeptide A8 antibody
      • UDP glucuronosyltransferase 1 family polypeptide A8s antibody
      • UDP-glucuronosyltransferase 1-8 antibody
      • UDP-glucuronosyltransferase 1-H antibody
      • UDP-glucuronosyltransferase 1A8 antibody
      • UDPGT 1-8 antibody
      • UDPGT antibody
      • UGT-1H antibody
      • UGT1*8 antibody
      • UGT1-08 antibody
      • UGT1.8 antibody
      • UGT1A8 antibody
      • UGT1A8S antibody
      • UGT1H antibody
      see all

    Images

    • Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling UGT1A8 with ab172624 at 1/250 dilution.

    • ab172624 showing -ve staining in Human skeletal muscle tissue.
    • ab172624 showing -ve staining in Human normal tonsil tissue.
    • Immunofluorescent analysis of SW480 cells labeling UGT1A8 with ab172624 at 1/100 dilution (red). DAPI nuclear staining (blue).

    • All lanes : Anti-UGT1A8 antibody [EPR11949] (ab172624) at 1/1000 dilution

      Lane 1 : HT-29 cell lysate
      Lane 2 : SW480 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 60 kDa

    References

    This product has been referenced in:
    • Zhou X  et al. Resveratrol represses estrogen-induced mammary carcinogenesis through NRF2-UGT1A8-estrogen metabolic axis activation. Biochem Pharmacol 155:252-263 (2018). Read more (PubMed: 30009768) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab172624.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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