Anti-UGT2A1 antibody (ab126527)

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Overview

  • Product name

    Anti-UGT2A1 antibody

  • Description

    Rabbit polyclonal to UGT2A1

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    antigen sequence: KEHNVTVLVA SGALFITPTS NPSLTFEIYK VPFGKERIEG VIKDFVLTWL ENRPSPSTIW RFYQEMAKVI KDFHMVSQEI CDGVLKNQQL MAKLKKSKFE VLVSDPVFPC GDIVALKLGI PFMYS, corresponding to amino acids in Human UGT2A1.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Human nasopharynx tissue

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126527 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium.

  • Tissue specificity

    Olfactory epithelium and brain. Isoform 2 is mainly expressed in the nasal mucosa.

  • Sequence similarities

    Belongs to the UDP-glycosyltransferase family.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • UD2A1_HUMAN antibody
      • UDP glucuronosyltransferase 2 family polypeptide A1 complex locus antibody
      • UDP glycosyltransferase 2 family polypeptide A1 antibody
      • UDP-glucuronosyltransferase 2A1 antibody
      • UDPGT 2A1 antibody
      • Ugt2a1 antibody
      • UGT2A2 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UGT2A1 antibody (ab126527)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UGT2A1 antibody (ab126527)
      ab126527, at 1/20 dilution, staining UGT2A1 in paraffin-embedded Human nasopharynx tissue by Immunohistochemistry.

    References

    ab126527 has not yet been referenced specifically in any publications.

    Publishing research using ab126527? Please let us know so that we can cite the reference in this datasheet.

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