Overview

  • Product name

    Anti-UGT2B15 antibody [EPR10615(B)]
    See all UGT2B15 primary antibodies
  • Description

    Rabbit monoclonal [EPR10615(B)] to UGT2B15
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues within Human UGT2B15 (Uniprot ID P54855).

  • Positive control

    • LnCaP cell lysate
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab154864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 61 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
    • Tissue specificity

      Expressed in many tissues. Present in liver, prostate and testis.
    • Sequence similarities

      Belongs to the UDP-glycosyltransferase family.
    • Cellular localization

      Microsome membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • EC 2.4.1.17 antibody
      • HLUG4 antibody
      • UDB15_HUMAN antibody
      • UDP glucuronosyltransferase 2 family polypeptide B15 antibody
      • UDP glucuronosyltransferase 2 family, member B15 antibody
      • UDP glucuronosyltransferase 2 family, member B8 antibody
      • UDP glucuronosyltransferase 2B15 antibody
      • UDP glucuronosyltransferase UGT2B15 antibody
      • UDP glucuronyltransferase family 2 beta 15 antibody
      • UDP glycosyltransferase 2 family, member B15 antibody
      • UDP glycosyltransferase 2B15 antibody
      • UDP-glucuronosyltransferase 2B15 antibody
      • UDP-glucuronosyltransferase 2B8 antibody
      • UDPGT 2B15 antibody
      • UDPGT 2B8 antibody
      • UDPGT2B15 antibody
      • UDPGTh 3 antibody
      • UDPGTh-3 antibody
      • UDPGTH3 antibody
      • UGT2B15 antibody
      • UGT2B8 antibody
      • Uridine diphosphate glucuronosyltransferase 2 family, member B8 antibody
      • Uridine diphosphate glycosyltransferase 2 family, member B15 antibody
      see all

    Images

    • Anti-UGT2B15 antibody [EPR10615(B)] (ab154864) at 1/1000 dilution + LnCap cell lysate at 10 µg

      Predicted band size: 61 kDa

    References

    This product has been referenced in:

    • Chen X  et al. Bioinformatic analysis suggests that UGT2B15 activates the Hippo-YAP signaling pathway leading to the pathogenesis of gastric cancer. Oncol Rep 40:1855-1862 (2018). Read more (PubMed: 30066917) »
    • Shukla S  et al. Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance. Cancer Cell 32:792-806.e7 (2017). Read more (PubMed: 29153843) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab154864.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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