UNC 1215, L3MBTL3 methyllysine reader domain antagonist (ab144664)

Overview

  • Product name
    UNC 1215, L3MBTL3 methyllysine reader domain antagonist
  • Description
    Potent, selective L3MBTL3 methyllysine (Kme) reader domain antagonist
  • Biological description
    Potent, selective L3MBTL3 methyllysine (Kme) reader domain antagonist (IC50 = 40 nM; Kd = 120 nM). Interacts with apoptotic Bcl-2 transcription factor BCLAF1. Antitumor agent. Active in vitro.
  • Purity
    > 97%
  • CAS Number
    1415800-43-9
  • Chemical structure
    Chemical Structure

Properties

  • Chemical name
    1,1'-[2-(Phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone
  • Molecular weight
    529.72
  • Molecular formula
    C32H43N5O2
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in 2eq. HCl to 100 mM, in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    O=C(N1CCC(CC1)N2CCCC2)c4ccc(c(Nc3ccccc3)c4)C(=O)N5CCC(CC5)N6CCCC6
  • Source

    Synthetic

References

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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