Anti-Unc93a antibody (ab69443)
Key features and details
- Rabbit polyclonal to Unc93a
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Unc93a antibody -
Description
Rabbit polyclonal to Unc93a -
Host species
Rabbit -
Specificity
ab69443 will not cross-react with Unc93b. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
An 18 amino acid synthetic peptide from near the carboxy terminus of human Unc93a.
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Positive control
- HeLa cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab69443 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 51 kDa).
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Notes |
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WB
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 51 kDa). |
Target
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Relevance
Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a and its function is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary. Two isoforms of Unc93a are known to exist. -
Cellular localization
Cell membrane; Multi-pass membrane protein. -
Database links
- Entrez Gene: 54346 Human
- Omim: 607995 Human
- SwissProt: Q86WB7 Human
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Alternative names
- dJ366N23.1 (putative C. elegans UNC-93 (protein 1, C46F11.1) LIKE) antibody
- dJ366N23.1 antibody
- dJ366N23.2 antibody
see all
Images
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Lane 1 : Anti-Unc93a antibody (ab69443) at 0.5 µg/ml
Lane 2 : Anti-Unc93a antibody (ab69443) at 1 µg/ml
All lanes : HeLa cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 51 kDa
Observed band size: 48 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab69443 has been referenced in 2 publications.
- Ceder MM et al. Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster. Front Cell Dev Biol 8:579 (2020). PubMed: 32733888
- Ceder MM et al. The Neuronal and Peripheral Expressed Membrane-Bound UNC93A Respond to Nutrient Availability in Mice. Front Mol Neurosci 10:351 (2017). PubMed: 29163028