Overview

  • Product name

    Anti-Unc93a antibody
  • Description

    Rabbit polyclonal to Unc93a
  • Host species

    Rabbit
  • Specificity

    ab69443 will not cross-react with Unc93b.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    An 18 amino acid synthetic peptide from near the carboxy terminus of human Unc93a.

  • Positive control

    • HeLa cell lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab69443 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 51 kDa).

Target

  • Relevance

    Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a and its function is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary. Two isoforms of Unc93a are known to exist.
  • Cellular localization

    Cell membrane; Multi-pass membrane protein.
  • Database links

  • Alternative names

    • dJ366N23.1 (putative C. elegans UNC-93 (protein 1, C46F11.1) LIKE) antibody
    • dJ366N23.1 antibody
    • dJ366N23.2 antibody
    • dJ366N23.2 (putative C. elegans UNC-93 (protein 1, C46F11.1) C-terminal LIKE) antibody
    • HmUNC 93A antibody
    • MGC119395 antibody
    • MGC119397 antibody
    • Protein unc 93 homolog A antibody
    • Protein UNC 93A antibody
    • unc 93 homolog A (C. elegans) antibody
    • Unc 93A antibody
    • Unc93 homolog A antibody
    see all

Images

  • Lane 1 : Anti-Unc93a antibody (ab69443) at 0.5 µg/ml
    Lane 2 : Anti-Unc93a antibody (ab69443) at 1 µg/ml

    All lanes : HeLa cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 51 kDa
    Observed band size: 48 kDa
    why is the actual band size different from the predicted?

References

This product has been referenced in:

  • Ceder MM  et al. The Neuronal and Peripheral Expressed Membrane-Bound UNC93A Respond to Nutrient Availability in Mice. Front Mol Neurosci 10:351 (2017). Read more (PubMed: 29163028) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for your enquiry. The exact immunogen sequence is proprietary. Sequential homology between antigen of ab69443 and mouse Unc93a (SwissProt; Q710D3) is 25%. Unfortunately, there is not good probability for ab69443 reacting with sample from mouse. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

Read More

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