Key features and details
- Rabbit polyclonal to UNC93B1
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-UNC93B1 antibody
See all UNC93B1 primary antibodies
DescriptionRabbit polyclonal to UNC93B1
Specificityab69497 will not crossreact with Unc93A.
Tested applicationsSuitable for: ICC/IF, IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human UNC93B1 (N terminal).
- Human heart tissue lysate.
This product was previously labelled as UNC93B
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab69497 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|IHC-P||Use a concentration of 2.5 µg/ml.|
|WB||Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).|
RelevanceUNC93B is a protein with similarity to the C. elegans unc93 protein. The Unc93 protein is involved in the regulation or coordination of muscle contraction in the worm. Defects in UNC93B are associated with susceptibility to herpes simplex encephalitis (HSE) which is a rare complication of human herpesvirus 1 (HHV-1) infection.
Cellular localizationMembrane; Multi pass membrane protein
- hUNC93B1 antibody
- IIAE1 antibody
- Protein unc 93 homolog B1 antibody
Lane 1 : Anti-UNC93B1 antibody (ab69497) at 0.5 µg/ml
Lane 2 : Anti-UNC93B1 antibody (ab69497) at 1 µg/ml
All lanes : human heart
Lysates/proteins at 15 µg per lane.
All lanes : Anti-rabbit
Predicted band size: 67 kDa
Observed band size: 67 kDa
ab69497 at 2.5 µg/ml staining UNC93B1 in human heart tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).
Immunofluorescence of UNC93B1 in Human Heart cells using ab69497 at 20 ug/ml.
ab69497 has been referenced in 1 publication.
- Garcia-Cattaneo A et al. Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling. Proc Natl Acad Sci U S A 109:9053-8 (2012). PubMed: 22611194