Overview

  • Product name

    Anti-UNCX antibody
  • Description

    Rabbit polyclonal to UNCX
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to Human UNCX aa 173-236.
    Sequence:

    PAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLHSP GGLSLHSAPSSDSD


    Database link: A6NJT0

  • Positive control

    • ICC/IF: NB-4 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab221353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Target

  • Function

    Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.
  • Sequence similarities

    Belongs to the paired homeobox family. Unc-4 subfamily.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Homeobox protein unc-4 homolog antibody
    • Homeobox protein Uncx4.1 antibody
    • tcag7.1272 antibody
    • UNC homeobox antibody
    • Unc4.1 homeobox antibody
    • UNC4_HUMAN antibody
    • Uncx antibody
    • UNCX4.1 antibody
    see all

Images

  • Immunfluorescent analysis of PFA fixed, Triton X-100 permeabilized NB-4 cells labeling UNCX with ab221353 at 4 µg/mL (green).

References

ab221353 has not yet been referenced specifically in any publications.

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