Key features and details
- Rabbit polyclonal to Unrip
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Unrip antibody
See all Unrip primary antibodies
DescriptionRabbit polyclonal to Unrip
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant protein fragment, corresponding to a region within amino acids 25-289 of Human Unrip (AAH00162).
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab102001 in the following tested applications.
|WB||1/500 - 1/3000. Predicted molecular weight: 38 kDa.|
FunctionThe SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
Sequence similaritiesBelongs to the WD repeat STRAP family.
Contains 7 WD repeats.
Cellular localizationCytoplasm. Nucleus. Localized predominantly in the cytoplasm but also found in the nucleus.
- Information by UniProt
- MAP activator with WD repeats antibody
- MAWD antibody
- PTWD antibody
ab102001 has been referenced in 1 publication.
- Pruksakorn D et al. Oncogenic roles of serine-threonine kinase receptor-associated protein (STRAP) in osteosarcoma. Cancer Chemother Pharmacol 82:1039-1047 (2018). PubMed: 30276452