ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Su B et al. Identification of potential targets for diallyl disulfide in human gastric cancer MGC-803 cells using proteomics approaches. Oncol Rep33:2484-94 (2015).
Read more (PubMed: 25812569) »