Overview

  • Product name

    Anti-uPA Receptor/U-PAR antibody [VIM5]
    See all uPA Receptor/U-PAR primary antibodies
  • Description

    Mouse monoclonal [VIM5] to uPA Receptor/U-PAR
  • Host species

    Mouse
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to uPA Receptor/U-PAR. Human myeloid cell line THP-1.

  • Positive control

    • Flow Cytometry: Human peripheral blood cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab234179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Target

  • Function

    Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
  • Tissue specificity

    Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
  • Sequence similarities

    Contains 3 UPAR/Ly6 domains.
  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD 87 antibody
    • CD87 antibody
    • CD87 antigen antibody
    • MO 3 antibody
    • MO3 antibody
    • Monocyte activation antigen Mo3 antibody
    • Plasminogen activator receptor urokinase antibody
    • Plasminogen activator urokinase receptor antibody
    • PLAUR antibody
    • U PAR antibody
    • u plasminogen activator receptor antibody
    • U-PAR antibody
    • u-plasminogen activator receptor form 2 antibody
    • UPA receptor antibody
    • uPAR antibody
    • UPAR_HUMAN antibody
    • Urinary plasminogen activator receptor antibody
    • URKR antibody
    • Urokinase plasminogen activator receptor antibody
    • Urokinase plasminogen activator surface receptor antibody
    • urokinase-type plasminogen activator (uPA) receptor antibody
    see all

Images

  • Surface staining of human peripheral blood cells with ab234179, followed by a Goat anti-mouse-APC conjugated secondary. Gated on lymphocytes.

References

ab234179 has not yet been referenced specifically in any publications.

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