Recombinant
RabMAb

Recombinant Anti-UPB1 antibody [EPR9133(B)] (ab140622)

Overview

  • Product name

    Anti-UPB1 antibody [EPR9133(B)]
    See all UPB1 primary antibodies
  • Description

    Rabbit monoclonal [EPR9133(B)] to UPB1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, IPmore details
    Unsuitable for: Flow Cyt or ICC
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human UPB1 aa 350-450 (C terminal). The exact sequence is proprietary.

  • Positive control

    • Human fetal liver tissue lysate; Human kidney tissue.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab140622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Predicted molecular weight: 43 kDa.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt or ICC.
  • Target

    • Relevance

      UPB1, also known as beta ureidopropionase, belongs to the CN hydrolase family. It catalyzes the last step in the pyrimidine degradation pathway in which the pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively.
    • Cellular localization

      Cytoplasmic
    • Database links

    • Alternative names

      • AI195023 antibody
      • Beta alanine synthase antibody
      • Beta ureidopropionase antibody
      • BUP1 antibody
      • N carbamoyl beta alanine amidohydrolase antibody
      • Ureidopropionase antibody
      • Ureidopropionase, beta antibody
      see all

    Images

    • Anti-UPB1 antibody [EPR9133(B)] (ab140622) at 1/10000 dilution + Human fetal liver tissue lysate at 10 µg

      Predicted band size: 43 kDa

    • Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling UPB1 with ab140622 at 1/100 dilution.

      Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    References

    ab140622 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab140622.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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