Overview

  • Product name

    Ursolic acid, Pentacyclic triterpenoid
  • Description

    Pentacyclic triterpenoid; antitumourigenic.
  • Biological description

    Pentacyclic triterpenoid. Suppresses NF-κB activation in vitro. Antitumourigenic, antiangiogenic, anti-inflammatory and proapoptotic effects.
  • Purity

    > 99%
  • CAS Number

    77-52-1
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Kim SH  et al. Ursolic acid, a potential PPAR? agonist, suppresses ovalbumin-induced airway inflammation and Penh by down-regulating IL-5, IL-13, and IL-17 in a mouse model of allergic asthma. Eur J Pharmacol : (2012). Read more (PubMed: 23201068) »
  • Pathak AK  et al. Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells. Mol Cancer Res 5:943-55 (2007). Read more (PubMed: 17855663) »
  • Shishodia S  et al. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1. Cancer Res 63:4375-83 (2003). Read more (PubMed: 12907607) »

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