Overview

  • Product name
    Anti-US12 antibody [H1113]
  • Description
    Mouse monoclonal [H1113] to US12
  • Host species
    Mouse
  • Specificity

    ab53480m reacts with US12.

  • Tested applications
    Suitable for: ICC/IF, WB, IPmore details
  • Species reactivity
    Reacts with: Other species
  • Immunogen

    Synthetic peptide corresponding to Herpes simplex virus US12.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    H1113
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab53480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 10 µg/ml. Predicted molecular weight: 55 kDa.
IP Use at an assay dependent dilution. PubMed: 19321610

Target

  • Relevance
    Herpes simplex virus (HSV) ICP27 (Infected cell polypeptide 27) is an essential and multifunctional regulator of viral gene expression that modulates RNA splicing, polyadenylation, and nuclear export. ICP27 Belongs to the herpesviruses UL69 family. It is involved in the down-regulation of viral immediate-early genes and acts in combination with ICP0 and ICP4 as an activator of late genes.
  • Alternative names
    • ICP47 protein antibody
    • Immediate early protein IE12 antibody
    • Infected cell protein 47 antibody
    • US12 antibody
    • US12 protein antibody
    see all

References

This product has been referenced in:
  • Zhang M  et al. Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4. Front Immunol 9:2932 (2018). Read more (PubMed: 30619292) »
  • Zhao Z  et al. CDK9 and SPT5 proteins are specifically required for expression of herpes simplex virus 1 replication-dependent late genes. J Biol Chem 292:15489-15500 (2017). Read more (PubMed: 28743741) »
See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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