Overview

  • Product name

  • Description

    Rabbit polyclonal to USF1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Rabbit, Cow
  • Immunogen

    Recombinant full length protein corresponding to Human USF1 aa 1-310.
    Sequence:

    MKGQQKTAET EEGTVQIQEG AVATGEDPTS VAIASIQSAA TFPDPNVKYV FRTENGGQVM YRVIQVSEGQ LDGQTEGTGA ISGYPATQSM TQAVIQGAFT SDDAVDTEGT AAETHYTYFP STAVGDGAGG TTSGSTAAVV TTQGSEALLG QATPPGTGQF FVMMSPQEVL QGGSQRSIAP RTHPYSPKSE APRTTRDEKR RAQHNEVERR RRDKINNWIV QLSKIIPDCS MESTKSGQSK GGILSKACDY IQELRQSNHR LSEELQGLDQ LQLDNDVLRQ QVEDLKNKNL LLRAQLRHHG LEVVIKNDSN


    Database link: P22415

  • Positive control

    • K562 cell line extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab180717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
IHC-P 1/50 - 1/200.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

WB 1/500 - 1/200. Predicted molecular weight: 34 kDa.

Target

  • Relevance

    USF1 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E box motifs. USF1 has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this.
  • Cellular localization

    Nuclear
  • Database links

  • Alternative names

    • bHLHb11 antibody
    • Class B basic helix-loop-helix protein 11 antibody
    • FCHL 1 antibody
    • FCHL antibody
    • FCHL1 antibody
    • HGNC:12593 antibody
    • HYPLIP 1 antibody
    • HYPLIP1 antibody
    • Major late transcription factor 1 antibody
    • Major late transcription factor antibody
    • MLTF antibody
    • MLTF I antibody
    • MLTFI antibody
    • Transcription factor USF-1 antibody
    • UEF antibody
    • Upstream stimulatory factor 1 antibody
    • Upstream transcription factor 1 antibody
    • Upstream transcription factor 1, isoform CRA_a antibody
    • USF 1 antibody
    • USF antibody
    see all

Images

  • Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab180717. Blue DAPI for nuclear staining.
  • Anti-USF1 antibody (ab180717) at 1/500 dilution + K562 cell line extract

    Predicted band size: 34 kDa

References

This product has been referenced in:

  • Wang W  et al. Upstream transcription factor 1 prompts malignancies of cervical cancer primarily by transcriptionally activating p65 expression. Exp Ther Med 16:4415-4422 (2018). Read more (PubMed: 30542391) »
See 1 Publication for this product

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