Key features and details
- Rabbit polyclonal to USH1G
- Suitable for: WB, ICC/IF, ICC
- Reacts with: Human
- Isotype: IgG
Product nameAnti-USH1G antibody
See all USH1G primary antibodies
DescriptionRabbit polyclonal to USH1G
Tested applicationsSuitable for: WB, ICC/IF, ICCmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide within Human USH1G (internal sequence). The exact sequence is proprietary.
Database link: Q495M9
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferConstituents: 1.21% Tris, 0.75% Glycine
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab196350 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 51 kDa.|
|ICC/IF||1/200 - 1/1000.|
|ICC||1/200 - 1/1000.|
FunctionRequired for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Tissue specificityExpressed in vestibule of the inner ear, eye and small intestine.
Involvement in diseaseUsher syndrome 1G
Sequence similaritiesContains 3 ANK repeats.
Contains 1 SAM (sterile alpha motif) domain.
Cellular localizationCytoplasm > cytosol. Cytoplasm > cytoskeleton. Cell membrane. Detected at the tip of cochlear hair cell stereocilia. Recruited to the cell membrane via interaction with CDH23 or PCDH15.
- Information by UniProt
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ab196350 has not yet been referenced specifically in any publications.