Overview

  • Product name
    Anti-USP19 antibody
    See all USP19 primary antibodies
  • Description
    Rabbit polyclonal to USP19
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide derived from internal sequence of Human USP19.

  • Positive control
    • NIH3T3 cell extract; Human heart tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab167059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 146 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates.
  • Sequence similarities
    Belongs to the peptidase C19 family.
    Contains 2 CS domains.
    Contains 1 MYND-type zinc finger.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • 8430421I07Rik antibody
    • AI047774 antibody
    • Deubiquitinating enzyme 19 antibody
    • Ubiquitin carboxyl terminal hydrolase 19 antibody
    • Ubiquitin carboxyl-terminal hydrolase 19 antibody
    • Ubiquitin specific peptidase 19 antibody
    • Ubiquitin specific processing protease 19 antibody
    • Ubiquitin specific protease 19 antibody
    • Ubiquitin thioesterase 19 antibody
    • Ubiquitin thiolesterase 19 antibody
    • Ubiquitin-specific-processing protease 19 antibody
    • UBP19_HUMAN antibody
    • Usp19 antibody
    • Zinc finger MYND domain containing protein 9 antibody
    • Zinc finger MYND domain-containing protein 9 antibody
    • ZMYND9 antibody
    see all

Images

  • Western blot - Anti-USP19 antibody (ab167059)
    Western blot - Anti-USP19 antibody (ab167059)
    All lanes : Anti-USP19 antibody (ab167059) at 1/500 dilution

    Lane 1 : NIH3T3 cell extract
    Lane 2 : NIH3T3 cell extract with immunizing peptide

    Predicted band size: 146 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP19 antibody (ab167059)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP19 antibody (ab167059)
    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labeling USP19 with ab167059 at 5 µg/ml.

References

ab167059 has not yet been referenced specifically in any publications.

Publishing research using ab167059? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Submit a review Submit a question

There are currently no Customer reviews or Questions for ab167059.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up