Anti-USP19 antibody (ab167059)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-USP19 antibody
See all USP19 primary antibodies -
DescriptionRabbit polyclonal to USP19
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Host speciesRabbit
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Tested applicationsSuitable for: WB, IHC-Pmore details
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Species reactivityReacts with: Mouse, Rat, Human
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Immunogen
Synthetic peptide derived from internal sequence of Human USP19.
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Positive control
- NIH3T3 cell extract; Human heart tissue.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
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Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
Note: PBS without Mg2+ and Ca2+. -
Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab167059 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/1000. Predicted molecular weight: 146 kDa. | |
| IHC-P | Use a concentration of 5 µg/ml. |
Target
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FunctionDeubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates.
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Sequence similaritiesBelongs to the peptidase C19 family.
Contains 2 CS domains.
Contains 1 MYND-type zinc finger. -
Post-translational
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR. -
Cellular localizationEndoplasmic reticulum membrane.
- Information by UniProt
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Database links
- Entrez Gene: 10869 Human
- Entrez Gene: 71472 Mouse
- Entrez Gene: 361190 Rat
- Omim: 614471 Human
- SwissProt: O94966 Human
- SwissProt: Q3UJD6 Mouse
- SwissProt: Q6J1Y9 Rat
- Unigene: 255596 Human
see all -
Alternative names
- 8430421I07Rik antibody
- AI047774 antibody
- Deubiquitinating enzyme 19 antibody
see all
Images
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Western blot - Anti-USP19 antibody (ab167059)All lanes : Anti-USP19 antibody (ab167059) at 1/500 dilution
Lane 1 : NIH3T3 cell extract
Lane 2 : NIH3T3 cell extract with immunizing peptide
Predicted band size: 146 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP19 antibody (ab167059)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labeling USP19 with ab167059 at 5 µg/ml.
Datasheets and documents
References
ab167059 has not yet been referenced specifically in any publications.
