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Rabbit polyclonal to USP19
Mouse, Rat, Human
Synthetic peptide derived from internal sequence of Human USP19.
NIH3T3 cell extract; Human heart tissue.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Preservative: 0.02% Sodium azide Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride Note: PBS without Mg 2+ and Ca 2+.
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 146 kDa.
Use a concentration of 5 µg/ml.
Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates.
Belongs to the peptidase C19 family.
Contains 2 CS domains. Contains 1 MYND-type zinc finger.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Endoplasmic reticulum membrane.
Information by UniProt
Deubiquitinating enzyme 19 antibody
Western blot - Anti-USP19 antibody (ab167059)
All lanes : Anti-USP19 antibody (ab167059) at 1/500 dilution Lane 1 : NIH3T3 cell extract Lane 2 : NIH3T3 cell extract with immunizing peptide Predicted band size: 146 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP19 antibody (ab167059)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labeling USP19 with ab167059 at 5 µg/ml.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"