Anti-USP37 antibody (ab190184)
Key features and details
- Rabbit polyclonal to USP37
- Suitable for: WB
- Reacts with: Mouse, Rat, Human, Xenopus laevis
- Isotype: IgG
Overview
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Product name
Anti-USP37 antibody
See all USP37 primary antibodies -
Description
Rabbit polyclonal to USP37 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human, Xenopus laevis -
Immunogen
Recombinant fragment corresponding to Human USP37 aa 1-300.
Database link: Q86T82 -
Positive control
- U2OS cells transfected with USP37 siRNA lysate, Mouse embryo fibroblasts cell lysate and INS1 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide -
Concentration information loading... -
Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab190184 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/2000. Predicted molecular weight: 110 kDa.
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| Notes |
|---|
|
WB
1/2000. Predicted molecular weight: 110 kDa. |
Target
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Tissue specificity
Expressed in brain and prostate. -
Sequence similarities
Belongs to the peptidase C19 family.
Contains 3 UIM (ubiquitin-interacting motif) repeats. - Information by UniProt
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Database links
- Entrez Gene: 57695 Human
- Entrez Gene: 319651 Mouse
- Entrez Gene: 316522 Rat
- SwissProt: Q86T82 Human
- SwissProt: Q8C0R0 Mouse
- Unigene: 166068 Human
- Unigene: 471601 Mouse
- Unigene: 66568 Mouse
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Alternative names
- Deubiquitinating enzyme 3 antibody
- Deubiquitinating enzyme 37 antibody
- EC 3.1.2.15 antibody
see all
Images
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Western blot - Anti-USP37 antibody (ab190184)All lanes : Anti-USP37 antibody (ab190184) at 1/2000 dilution
Lane 1 : Human U2OS cell lysate si Control
Lane 2 : Human U2OS cells transfected with USP37 siRNA
Lane 3 : Mouse Embryo Fibroblaste cell Lysate
Lane 4 : Rat INS1 cell lysate
Lysates/proteins at 40 µg per lane.
Predicted band size: 110 kDa -
Western blot - Anti-USP37 antibody (ab190184)All lanes : Anti-USP37 antibody (ab190184) at 1/2000 dilution
Lane 1 : Xenopus laevis crude egg extracts
Lysates/proteins at 50 µg per lane.
Predicted band size: 110 kDa
Datasheets and documents
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Datasheet download
References (4)
ab190184 has been referenced in 4 publications.
- Li W et al. Intermittent hypoxia-induced downregulation of microRNA-320b promotes lung cancer tumorigenesis by increasing CDT1 via USP37. Mol Ther Nucleic Acids 24:528-541 (2021). IHC-P ; Human . PubMed: 33898105
- Hong K et al. USP37 promotes deubiquitination of HIF2a in kidney cancer. Proc Natl Acad Sci U S A N/A:N/A (2020). WB ; Human . PubMed: 32461361
- Xiao Z et al. USP37 is a SNAI1 deubiquitinase. Am J Cancer Res 9:2749-2759 (2019). WB ; Human . PubMed: 31911859
- Hernández-Pérez S et al. USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication. Mol Oncol N/A:N/A (2016). WB ; Human . PubMed: 27296872
