Recombinant
RabMAb

Recombinant Anti-USP4 antibody [EPR13846] - BSA and Azide free (ab250352)

Overview

  • Product name

    Anti-USP4 antibody [EPR13846] - BSA and Azide free
    See all USP4 primary antibodies
  • Description

    Rabbit monoclonal [EPR13846] to USP4 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    within Human USP4 aa 900 to the C-terminus. The exact sequence is proprietary.
    Database link: Q13107

  • General notes

    Ab250352 is the carrier-free version of ab181105. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab250352 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab250352 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 109 kDa.

Target

  • Function

    Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. Plays a role in the regulation of quality control in the ER.
  • Tissue specificity

    Overexpressed in small cell tumors and adenocarcinomas of the lung compared to wild-type lung (at protein level). Expressed in the hippocampal neurons.
  • Sequence similarities

    Belongs to the peptidase C19 family. USP4 subfamily.
    Contains 1 DUSP domain.
  • Post-translational
    modifications

    Monoubiquitinated by TRIM21. Ubiquitination does not lead to its proteasomal degradation. Autodeubiquitinated.
  • Cellular localization

    Cytoplasm. Nucleus. Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The relative amounts found in the nucleus and cytoplasm vary according to the cell type.
  • Information by UniProt
  • Database links

  • Alternative names

    • Deubiquitinating enzyme 4 antibody
    • MGC149848 antibody
    • MGC149849 antibody
    • Proto oncogene antibody
    • Protooncogene antibody
    • Ubiquitin carboxyl terminal hydrolase 4 antibody
    • Ubiquitin carboxyl-terminal hydrolase 4 antibody
    • Ubiquitin specific peptidase 4 (proto oncogene) antibody
    • Ubiquitin specific peptidase 4 (protooncogene) antibody
    • Ubiquitin specific peptidase 4 antibody
    • Ubiquitin specific processing protease 4 antibody
    • Ubiquitin specific protease 4 (proto oncogene) antibody
    • Ubiquitin specific protease 4 (protooncogene) antibody
    • Ubiquitin specific protease 4 antibody
    • Ubiquitin specific protease proto oncogene antibody
    • Ubiquitin specific protease protooncogene antibody
    • Ubiquitin thioesterase 4 antibody
    • Ubiquitin thiolesterase 4 antibody
    • Ubiquitin-specific-processing protease 4 antibody
    • Ubiquitous nuclear protein homolog antibody
    • UBP4_HUMAN antibody
    • UNP antibody
    • UNPH antibody
    • USP 4 antibody
    • USP4 antibody
    see all

References

ab250352 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab250352.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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