Anti-Uteroglobin antibody (ab40873)
Key features and details
- Rabbit polyclonal to Uteroglobin
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
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- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Uteroglobin antibody
See all Uteroglobin primary antibodies -
Description
Rabbit polyclonal to Uteroglobin -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Recombinant rat uteroglobin His fusion protein.
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General notes
This antibody is useful for distinguishing ciliated from non-ciliated cells in the adult mouse lung.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Primary antibody notes
This antibody is useful for distinguishing ciliated from non-ciliated cells in the adult mouse lung. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab40873 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | (3) |
1/1600.
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Notes |
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IHC-P
1/1600. |
Target
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Function
Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. -
Tissue specificity
Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways). -
Sequence similarities
Belongs to the secretoglobin family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 22287 Mouse
- SwissProt: Q06318 Mouse
- Unigene: 2258 Mouse
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Alternative names
- Blastokinin antibody
- CC10 antibody
- CC16 antibody
see all
Images
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Adult mouse lung was embedded in paraffin and stained with ab40873 (1:1600 dilution).
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ab40873 staining Uteroglobin in human lung parenchyma tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Tissue was fixed with formaldehyde and a heat mediated antigen retrieval step was performed using 10mM citrate buffer. Samples were then blocked with 1% BSA, 0.1% Triton-X/ PBS for 15 minutes at 18°C followed by incubation with the primary antibody at a 1/500 dilution for 16 hours at 4°C. An HRP-conjugated pig anti-rabbit polyclonal was used as secondary antibody at a 1/100 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (37)
ab40873 has been referenced in 37 publications.
- Munis AM et al. A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications. Mol Ther Methods Clin Dev 20:237-246 (2021). PubMed: 33426150
- Liu Y et al. Proteomic Analysis Revealed the Characteristics of Key Proteins Involved in the Regulation of Inflammatory Response, Leukocyte Transendothelial Migration, Phagocytosis, and Immune Process during Early Lung Blast Injury. Oxid Med Cell Longev 2021:8899274 (2021). PubMed: 34007409
- Bentley-Ford MR et al. A mouse model of BBS identifies developmental and homeostatic effects of BBS5 mutation and identifies novel pituitary abnormalities. Hum Mol Genet 30:234-246 (2021). PubMed: 33560420
- Lee H et al. mTORC1 is a mechanosensor that regulates surfactant function and lung compliance during ventilator-induced lung injury. JCI Insight 6:N/A (2021). PubMed: 34138757
- Rosigkeit S et al. Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancer. Int J Cancer 149:1670-1682 (2021). PubMed: 34331774