Overview

  • Product name

    Anti-v-cyclin antibody [94B]
  • Description

    Rat monoclonal [94B] to v-cyclin
  • Host species

    Rat
  • Tested applications

    Suitable for: IP, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Species independent
  • Immunogen

    Fusion protein corresponding to v-cyclin.

  • General notes

     This product was previously labelled as HHV8 Cyclin

     

Properties

Applications

Our Abpromise guarantee covers the use of ab12208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately 30 kDa.
ICC/IF Use at an assay dependent dilution.

Target

  • Relevance

    HHV8 is associated with the develpment of Kaposi's Sarcoma and a number of B cell lymphomas in AIDS patients. HHV8 encodes a viral (v) cyclin homologous to cellular D type cyclins, a class of positive cell cycle regulators that are physiologically modulated by the p27(Kip1) cell cycle inhibitor.
  • Alternative names

    • HHV 8 cyclin antibody
    • HHV 8c antibody
    • Human Herpesvirus 8 ORF72 antibody
    • Kaposi's sarcoma associated herpesvirus antibody
    • KSHV ORF72 antibody
    • ORF 72 antibody
    see all

References

This product has been referenced in:

  • Nayar U  et al. Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies. J Clin Invest 127:2066-2080 (2017). Read more (PubMed: 28504647) »
  • Sharma-Walia N  et al. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol 88:2131-56 (2014). Read more (PubMed: 24335295) »
See all 4 Publications for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Question
Answer



Unfortunately, we do not have any information on this particular query.
We would suggest that publication related to this antibody may give some information but we do not know that there is anything specific.

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Question
Answer

Thank you for your telephone enquiry yesterday afternoon. As requested, here is a list of all our antibodies for detection of HHV8 virus. I can recommend to review the online datasheets for further information. ab4103 Rat monoclonal Anti-HHV8 antibody [LN35] Applications: IHC-Fr, IHC-P Click here (or use the following: https://www.abcam.com/index.html?datasheet=4103). ab12208 Rat monoclonal Anti-HHV8 Cyclin antibody [94B] Applications: IF, IP, WB Click here (or use the following: https://www.abcam.com/index.html?datasheet=12208). ab25122 Rabbit polyclonal Anti-HHV8 GPCR antibody Applications: Flow Cyt Click here (or use the following: https://www.abcam.com/index.html?datasheet=25122). ab16159 Sheep polyclonal Anti-HHV8 ORF62 antibody Applications: WB Click here (or use the following: https://www.abcam.com/index.html?datasheet=16159). I hope this will be helpful to you. If you have any further questions, please do not hesitate to contact us.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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