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Please advise which groups/ members of HDAC are inhibited by ab120745 Valproic acid.
Asked on Sep 22 2014
Unfortunately, we do not conduct scientific research within our labs and so we do not test the specific actions of our inhibitors. We simply produce this biochemical to a high quality.
I would suggest that your customer looks at the available literature for Valproic acid to see what other researchers have found through their research.
From my brief literature research, I have found that valproic acid inhibits both class I and II HDACs, with a high potency for class I HDACs.
Please see the following publication which may also be of interest to your customer:
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
Elisa ThomasAbcam Scientific Support
Answered on Sep 22 2014