Valsartan, Highly selective, , competitive AT1 receptor antagonist (ab141486)

Overview

  • Product name

    Valsartan, Highly selective, , competitive AT1 receptor antagonist
  • Description

    Highly selective, potent, competitive AT1 receptor antagonist
  • Biological description

    Highly selective, potent, competitive AT1 receptor antagonist (Ki = 2.38 nM). Shows antihypertensive effects in vivo. Shows central and peripheral effects. Orally active.
  • Purity

    > 98%
  • CAS Number

    137862-53-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Nagasawa K  et al. Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats. Hypertens Res : (2014). Read more (PubMed: 25209105) »
  • Yin Y  et al. Angiotensin II type 1 receptor blockade suppresses H2O2-induced retinal degeneration in photoreceptor cells. Cutan Ocul Toxicol :1-6 (2014). Read more (PubMed: 25430074) »
  • Nakamura K  et al. Angiotensin II acting on brain AT1 receptors induces adrenaline secretion and pressor responses in the rat. Sci Rep 4:7248 (2014). Read more (PubMed: 25431019) »

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