Key features and details
- Mouse polyclonal to VAMP8/EDB
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-VAMP8/EDB antibody
See all VAMP8/EDB primary antibodies
DescriptionMouse polyclonal to VAMP8/EDB
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Recombinant full length protein corresponding to Human VAMP8/EDB.
Previously labelled as VAMP8.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.4
Constituent: 2.68% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab89158 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 11 kDa.|
FunctionInvolved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes.
Sequence similaritiesBelongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.
- Information by UniProt
- EDB antibody
- Endobrevin antibody
- VAMP 8 antibody
Anti-VAMP8/EDB antibody (ab89158) at 1 µg/ml +
A431 whole cell lysate (ab7909) at 25 µg
Predicted band size: 11 kDa
Anti-VAMP8/EDB antibody (ab89158) at 1 µg/ml + Transfected 293T lysate at 25 µg
Predicted band size: 11 kDa
Observed band size: 11 kDa
ab89158 has been referenced in 2 publications.
- Pirooz SD et al. UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs. Proc Natl Acad Sci U S A 111:2716-21 (2014). WB, ICC/IF ; Human . PubMed: 24550300
- Messenger SW et al. Vesicle associated membrane protein 8 (VAMP8)-mediated zymogen granule exocytosis is dependent on endosomal trafficking via the constitutive-like secretory pathway. J Biol Chem 289:28040-53 (2014). PubMed: 25138214