Overview

  • Product name
    Anti-VAP1 antibody
    See all VAP1 primary antibodies
  • Description
    Goat polyclonal to VAP1
  • Host species
    Goat
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    DEDPSFYSADSIY

    with a Cysteine residue linker, corresponding to internal sequence amino acids 712-724 of Human VAP1 (NP_003725.1).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • Human liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab115574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/64000.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
  • Tissue specificity
    Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis.
  • Sequence similarities
    Belongs to the copper/topaquinone oxidase family.
  • Post-translational
    modifications
    Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
    N- and O-glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
    • AOC3 antibody
    • AOC3_HUMAN antibody
    • Copper amine oxidase antibody
    • HPAO antibody
    • Membrane copper amine oxidase antibody
    • Membrane primary amine oxidase antibody
    • Semicarbazide sensitive amine oxidase antibody
    • Semicarbazide-sensitive amine oxidase antibody
    • SSAO antibody
    • VAP-1 antibody
    • Vascular adhesion protein 1 antibody
    • VP97 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VAP1 antibody (ab115574)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VAP1 antibody (ab115574)
    ab115574, at 3.75µg/ml, staining VAP1 in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

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