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Anti-VAP1 antibody (ab115574)

  • Datasheet
  • SDS
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VAP1 antibody (ab115574)

    Key features and details

    • Goat polyclonal to VAP1
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Protein
    Recombinant Human VAP1 protein (ab129129)
    Secondary
    Product image
    Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)

    View more associated products

    Overview

    • Product name

      Anti-VAP1 antibody
      See all VAP1 primary antibodies
    • Description

      Goat polyclonal to VAP1
    • Host species

      Goat
    • Tested Applications & Species

      Application Species
      IHC-P
      Human
      See all applications and species data
    • Immunogen

      Synthetic peptide:

      DEDPSFYSADSIY

      with a Cysteine residue linker, corresponding to internal sequence amino acids 712-724 of Human VAP1 (NP_003725.1).
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
    • Positive control

      • Human liver tissue.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
    • Storage buffer

      pH: 7.30
      Preservative: 0.02% Sodium azide
      Constituents: 0.5% BSA, 99% Tris buffered saline
    • Concentration information loading...
    • Purity

      Protein G purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurology process
      • Neurodegenerative disease
      • Alzheimer's disease
      • Other
      • Signal Transduction
      • Cytoskeleton / ECM
      • Cell Adhesion
      • Cell Adhesion Molecules
      • Vascular
      • Signal Transduction
      • Cytoskeleton / ECM
      • Cell Adhesion
      • Cell Adhesion Molecules
      • Endothelial

    Associated products

    • Compatible Secondaries

      • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
      • Donkey Anti-Goat IgG H&L (HRP) (ab205723)
    • Isotype control

      • Goat IgG, polyclonal - Isotype Control (ab37373)
    • Positive Controls

      • Recombinant Human VAP1 protein (ab123541)
    • Recombinant Protein

      • Recombinant Human VAP1 protein (ab129129)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab115574 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    IHC-P
    Human
    All applications
    Mouse
    Rat
    Application Abreviews Notes
    IHC-P
    Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
    Notes
    IHC-P
    Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    Target

    • Function

      Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
    • Tissue specificity

      Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis.
    • Sequence similarities

      Belongs to the copper/topaquinone oxidase family.
    • Post-translational
      modifications

      Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
      N- and O-glycosylated.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession Q16853 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 8639 Human
      • Entrez Gene: 11754 Mouse
      • Entrez Gene: 29473 Rat
      • Omim: 603735 Human
      • SwissProt: Q16853 Human
      • SwissProt: O70423 Mouse
      • SwissProt: O08590 Rat
      • Unigene: 198241 Human
      • Unigene: 67281 Mouse
      • Unigene: 198327 Rat
      see all
    • Alternative names

      • Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
      • AOC3 antibody
      • AOC3_HUMAN antibody
      • Copper amine oxidase antibody
      • HPAO antibody
      • Membrane copper amine oxidase antibody
      • Membrane primary amine oxidase antibody
      • Semicarbazide sensitive amine oxidase antibody
      • Semicarbazide-sensitive amine oxidase antibody
      • SSAO antibody
      • VAP-1 antibody
      • Vascular adhesion protein 1 antibody
      • VP97 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VAP1 antibody (ab115574)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VAP1 antibody (ab115574)
      ab115574, at 3.75µg/ml, staining VAP1 in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

    Protocols

    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (1)

    Publishing research using ab115574? Please let us know so that we can cite the reference in this datasheet.

    ab115574 has been referenced in 1 publication.

    • Abu El-Asrar AM  et al. Association of HMGB1 with oxidative stress markers and regulators in PDR. Mol Vis 23:853-871 (2017). PubMed: 29259392

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