Key features and details
- Rabbit monoclonal  to VAPB - BSA and Azide free
- Suitable for: WB
- Reacts with: Human
Product nameAnti-VAPB antibody  - BSA and Azide free
See all VAPB primary antibodies
DescriptionRabbit monoclonal  to VAPB - BSA and Azide free
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human VAPB aa 1-132.
Database link: O95292
- WB: HepG2, A549, Jurkat cells.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferConstituent: 100% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab276052 in the following tested applications.
|WB||1/500 - 1/2000. Predicted molecular weight: 27 kDa.|
RelevanceVAPB contains 1 MSP domain and it may play a role in vesicle trafficking. Defects in VAPB are a cause of proximal adult autosomal dominant spinal muscular atrophy [MIM:182980]; also called late onset spinal muscular atrophy Finkel type. Spinal muscular atrophies are neurodegenerative disorders characterized by degeneration of lower motor neurons, leading to progressive paralysis muscular atrophy. This form is a late adult onset form of the disease (after age 20 years). The patients show a benign course, most of them remaining ambulatory 10 to 40 years after clinical onset.
Cellular localizationCell membrane; Single-pass type IV membrane. Intracytoplasmic membrane; Single-pass type IV membrane protein. Note: Present in the plasma membrane and in intracellular vesicles.
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All lanes : Anti-VAPB antibody  - BSA and Azide free (ab276052) at 1/500 dilution
Lane 1 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate
Lane 2 : A549 (human lung carcinoma cell line) whole cell lysate
Lane 3 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate
Lysates/proteins at 30 µg per lane.
All lanes : Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution
Predicted band size: 27 kDa
Developed using the Odyssey technique.
Performed under reducing conditions.
ab276052 has not yet been referenced specifically in any publications.