Anti-Varicella Zoster Virus IE62 antibody [8B11] (ab52554)
Key features and details
- Mouse monoclonal [8B11] to Varicella Zoster Virus IE62
- Suitable for: ICC/IF
- Reacts with: Varicella zoster virus
- Isotype: IgG1
Overview
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Product name
Anti-Varicella Zoster Virus IE62 antibody [8B11]
See all Varicella Zoster Virus IE62 primary antibodies -
Description
Mouse monoclonal [8B11] to Varicella Zoster Virus IE62 -
Host species
Mouse -
Specificity
ab52554 recognises Varicella zoaster virus immediate early protein IE62. -
Tested applications
Suitable for: ICC/IFmore details
Unsuitable for: WB -
Species reactivity
Reacts with: Varicella zoster virus -
Immunogen
Tissue, cells or virus corresponding to Varicella Zoster Virus IE62.
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Positive control
- ICC/IF: Human fibroblasts infected with Varicella Zoster virus.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: PBS -
Concentration information loading...
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Purity
Affinity purified -
Purification notes
Purity >95% IgG by SDS-PAGE. -
Clonality
Monoclonal -
Clone number
8B11 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab52554 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
1/200.
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Notes |
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ICC/IF
1/200. |
Target
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Relevance
Varicella Zoster Virus (VZV), a member of the human herpes virus family, causes two distinct clinical manifestations: childhood chickenpox(Varicella) and shingles (zoster). Varicella is the outcome of the primary infection with VZV, whereas, zoster is the result of VZV reactivation from latently infected sensory ganglia which occurs predominantly in aging and immunosuppressed individuals. VZV is closely related to the herpes simplex viruses (HSV), sharing much genome homology. The known envelope glycoproteins (gB, gC, gE, gH, gI, gK, gL) correspond with those in HSV, however there is no equivalent of HSV gD. VZV virons are spherical and 150-200 nm in diameter. Its lipid envelope encloses the nucleocapsid of 162 capsomeres arranged in a hexagonal form. Its DNA is a single linear, double strand molecule, 125,000 nt long. The immediate-early protein IE62 is a major component of virus particles and initiates transcription from its own and other VZV gene promoters, acting synergistically with several viral and cellular transactivating proteins. -
Alternative names
- HHV3 antibody
- Human Herpesvirus 3 antibody
- IE62 antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab52554 has not yet been referenced specifically in any publications.