Description

  • Product name

    VAV3 peptide
  • Animal free

    No
  • Nature

    Synthetic
    • Sequence

      C-SGEQGTLKLPEK

Specifications

Our Abpromise guarantee covers the use of ab45613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

  • Reconstitution
    Reconstitute in 100µl sterile water.

General Info

  • Alternative names

    • FLJ40431
    • Guanine nucleotide exchange factor VAV3
    • Protein vav 3
    • Protein vav3
    • RGD1565941
    • VAV 3
    • Vav 3 guanine nucleotide exchange factor
    • VAV 3 oncogene
    • VAV 3 protein
    • VAV-3
    • Vav3
    • VAV3 oncogene
    • VAV3 protein
    • VAV3_HUMAN
    see all
  • Function

    Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
  • Sequence similarities

    Contains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • Information by UniProt

References

ab45613 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab45613.
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