Overview

  • Product name

    Anti-VAV3 (phospho Y173) antibody
    See all VAV3 primary antibodies
  • Description

    Rabbit polyclonal to VAV3 (phospho Y173)
  • Host species

    Rabbit
  • Specificity

    ab192590 detects endogenous levels of VAV3 only when phosphorylated at tyrosine 173.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human VAV3 (phospho Y173) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q9UKW4

  • Positive control

    • Extracts from Jurkat cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab192590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 98 kDa.

Target

  • Function

    Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
  • Sequence similarities

    Contains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ40431 antibody
    • Guanine nucleotide exchange factor VAV3 antibody
    • Protein vav 3 antibody
    • Protein vav3 antibody
    • RGD1565941 antibody
    • VAV 3 antibody
    • Vav 3 guanine nucleotide exchange factor antibody
    • VAV 3 oncogene antibody
    • VAV 3 protein antibody
    • VAV-3 antibody
    • Vav3 antibody
    • VAV3 oncogene antibody
    • VAV3 protein antibody
    • VAV3_HUMAN antibody
    see all

Images

  • All lanes : Anti-VAV3 (phospho Y173) antibody (ab192590) at 1/500 dilution

    Lane 1 : Extracts from Jurkat cells
    Lane 2 : Extracts from Jurkat cells with antigen-specific peptide

    Predicted band size: 98 kDa

References

ab192590 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab192590.
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