Product nameVCAM1 peptide
See all VCAM1 proteins and peptides
Amino Acid Sequence
Additional sequence informationCKGSYSLVEAQKSKV
Our Abpromise guarantee covers the use of ab156177 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-VCAM1 antibody [EPR5047] (ab134047)
Purity> 90 % n/a.
Blocking peptide of ab134047
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Information available upon request.
- CD106 Antigen
- INCAM 100
FunctionImportant in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Tissue specificityExpressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
Sequence similaritiesContains 7 Ig-like C2-type (immunoglobulin-like) domains.
DomainEither the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
- Information by UniProt
ab156177 has not yet been referenced specifically in any publications.