Anti-VDAC2 antibody - C-terminal (ab155803)
Key features and details
- Rabbit polyclonal to VDAC2 - C-terminal
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-VDAC2 antibody - C-terminal
See all VDAC2 primary antibodies -
Description
Rabbit polyclonal to VDAC2 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide, corresponding to a region within C terminal amino acids 233-294 of Human VDAC2 (Uniprot ID P45880)
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Positive control
- HepG2 and mouse liver whole cell lysate, methanol-fixed HeLa cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab155803 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (2) |
1/500 - 1/3000. Predicted molecular weight: 32 kDa.
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ICC/IF |
1/100 - 1/1000.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 32 kDa. |
ICC/IF
1/100 - 1/1000. |
Target
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Function
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. -
Tissue specificity
Expressed in all tissues examined. -
Sequence similarities
Belongs to the eukaryotic mitochondrial porin family. -
Domain
Consists mainly of a membrane-spanning beta-barrel formed by 19 beta-strands. -
Cellular localization
Mitochondrion outer membrane. - Information by UniProt
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Database links
- Entrez Gene: 7417 Human
- Entrez Gene: 22334 Mouse
- Omim: 193245 Human
- SwissProt: P45880 Human
- SwissProt: Q60930 Mouse
- Unigene: 355927 Human
- Unigene: 262327 Mouse
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Alternative names
- B-36 vdac antibody
- FLJ23841 antibody
- hVDAC2 antibody
see all
Images
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Anti-VDAC2 antibody - C-terminal (ab155803) at 1/1000 dilution + Mouse liver whole cell lysate at 50 µg
Predicted band size: 32 kDa
12% SDS PAGE -
Anti-VDAC2 antibody - C-terminal (ab155803) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 32 kDa
12% SDS PAGE -
Confocal immunofluorescence analysis of methanol-fixed HeLa cells labeling VDAC2 with ab155803 at 1/500 dilution (green). Alpha-tubulin filament labeling is shown in red.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab155803 has not yet been referenced specifically in any publications.