Key features and details
- Mouse monoclonal [FLT1658] to VEGF Receptor 1
- Suitable for: Flow Cyt, Functional Studies
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-VEGF Receptor 1 antibody [FLT1658]
See all VEGF Receptor 1 primary antibodies
DescriptionMouse monoclonal [FLT1658] to VEGF Receptor 1
Tested applicationsSuitable for: Flow Cyt, Functional Studiesmore details
Species reactivityReacts with: Human
Full length protein corresponding to Human VEGF Receptor 1.
Database link: P17948
- 293FT, A431 cells, cerebellum or skin cancer
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 0.05% BSA, PBS
Concentration information loading...
Purification notes200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G
Light chain typekappa
Our Abpromise guarantee covers the use of ab190712 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IF||Use a concentration of 1 - 2 µg/ml.|
|Flow Cyt||Use 1-2µg for 10 cells.|
|Functional Studies||Use at an assay dependent concentration.|
FunctionReceptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
Tissue specificityMostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. Specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. Isoform sFlt1 is strongly expressed in placenta.
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
- EC 220.127.116.11 antibody
- FLT 1 antibody
- FLT antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab190712 has not yet been referenced specifically in any publications.