Recombinant
RabMAb

Recombinant Anti-VGluT1 antibody [EPR10953] - C-terminal (ab180188)

Rabbit recombinant monoclonal VGluT1 antibody [EPR10953]. Validated in WB and tested in Mouse, Rat, Human. Cited in 3 publication(s).

Overview

  • Product name

    Anti-VGluT1 antibody [EPR10953] - C-terminal
    See all VGluT1 primary antibodies
  • Description

    Rabbit monoclonal [EPR10953] to VGluT1 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human VGluT1 aa 500 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: Q9P2U7

  • Positive control

    • Fetal brain, Neuro-2a and C6 lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab180188 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 61 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
    • Tissue specificity

      Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.
    • Sequence similarities

      Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
    • Cellular localization

      Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane. Cell junction, synapse, synaptosome.
    • Information by UniProt
    • Database links

    • Alternative names

      • BNPI antibody
      • Brain specific Na (+) dependent inorganic phosphate cotransporter antibody
      • Brain specific Na dependent inorganic phosphate cotransporter antibody
      • Brain-specific Na(+)-dependent inorganic phosphate cotransporter antibody
      • Slc17a7 antibody
      • Solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 antibody
      • Solute carrier family 17 member 7 antibody
      • Vesicular glutamate transporter 1 antibody
      • VGLU1_HUMAN antibody
      • VGLUT 1 antibody
      • VGluT1 antibody
      see all

    Images

    • All lanes : Anti-VGluT1 antibody [EPR10953] - C-terminal (ab180188) at 1/1000 dilution

      Lane 1 : Fetal brain lysate
      Lane 2 : Neuro-2a lysate
      Lane 3 : C6 lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 61 kDa

    References

    This product has been referenced in:

    • Zhou M  et al. Quantitative Proteomic Analysis Reveals Synaptic Dysfunction in the Amygdala of Rats Susceptible to Chronic Mild Stress. Neuroscience 376:24-39 (2018). WB . Read more (PubMed: 29452226) »
    • Lizarbe B  et al. Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet. Front Neurosci 12:985 (2018). Read more (PubMed: 30670942) »
    See all 4 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab180188.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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