Overview

  • Product name

    Anti-vGPCR antibody
  • Description

    Rabbit polyclonal to vGPCR
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Species independent
  • Immunogen

    Recombinant fragment corresponding to vGPCR aa 1-41 (N terminal).

  • General notes

     This product was previously labelled as HHV8 GPCR

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab25122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Relevance

    Kaposi's sarcoma-associated herpesvirus (KSHV, or human herpesvirus 8, HHV8), is a gamma herpesvirus that contain an open reading frame encoding a G protein-coupled receptor (GPCR) with putative 7 transmembrane domains. This GPCR has been shown to bind a number of chemokines including IL8, NAP2, PF4, MGSA/Gro alpha, I309, RANTES, MCP1, and MIP1 beta. The receptor is constitutively activated without chemokine binding, and it stimulates cell proliferation. KSHV GPCR is also a viral oncogene that stimulates angio-genesis through induction of VEGF expression. IP10, a chemokine, can inhibit constitutively activated KSHV GPCR.
  • Alternative names

    • Human Herpesvirus 8 GPCR antibody
    • Kaposi's sarcoma-associated herpesvirus GPCR antibody
    • KSHV GPCR antibody

References

ab25122 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Question
Answer

Thank you for your telephone enquiry yesterday afternoon. As requested, here is a list of all our antibodies for detection of HHV8 virus. I can recommend to review the online datasheets for further information. ab4103 Rat monoclonal Anti-HHV8 antibody [LN35] Applications: IHC-Fr, IHC-P Click here (or use the following: https://www.abcam.com/index.html?datasheet=4103). ab12208 Rat monoclonal Anti-HHV8 Cyclin antibody [94B] Applications: IF, IP, WB Click here (or use the following: https://www.abcam.com/index.html?datasheet=12208). ab25122 Rabbit polyclonal Anti-HHV8 GPCR antibody Applications: Flow Cyt Click here (or use the following: https://www.abcam.com/index.html?datasheet=25122). ab16159 Sheep polyclonal Anti-HHV8 ORF62 antibody Applications: WB Click here (or use the following: https://www.abcam.com/index.html?datasheet=16159). I hope this will be helpful to you. If you have any further questions, please do not hesitate to contact us.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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