Key features and details
- Rabbit polyclonal to vGPCR
- Suitable for: Flow Cyt
- Reacts with: Species independent
- Isotype: IgG
Product nameAnti-vGPCR antibody
DescriptionRabbit polyclonal to vGPCR
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Species independent
Recombinant fragment corresponding to vGPCR aa 1-41 (N terminal).
This product was previously labelled as HHV8 GPCR
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.1% Sodium azide
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab25122 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
RelevanceKaposi's sarcoma-associated herpesvirus (KSHV, or human herpesvirus 8, HHV8), is a gamma herpesvirus that contain an open reading frame encoding a G protein-coupled receptor (GPCR) with putative 7 transmembrane domains. This GPCR has been shown to bind a number of chemokines including IL8, NAP2, PF4, MGSA/Gro alpha, I309, RANTES, MCP1, and MIP1 beta. The receptor is constitutively activated without chemokine binding, and it stimulates cell proliferation. KSHV GPCR is also a viral oncogene that stimulates angio-genesis through induction of VEGF expression. IP10, a chemokine, can inhibit constitutively activated KSHV GPCR.
- Human Herpesvirus 8 GPCR antibody
- Kaposi's sarcoma-associated herpesvirus GPCR antibody
- KSHV GPCR antibody
ab25122 has not yet been referenced specifically in any publications.