Anti-Viperin antibody (ab208286)
Key features and details
- Rabbit polyclonal to Viperin
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Viperin antibody
See all Viperin primary antibodies -
Description
Rabbit polyclonal to Viperin -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Pig, Orangutan -
Immunogen
Recombinant fragment corresponding to Human Viperin aa 100-350.
Database link: Q8WXG1 -
Positive control
- Human brain lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab208286 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 3 µg/ml. Predicted molecular weight: 42 kDa.
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Notes |
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WB
Use a concentration of 3 µg/ml. Predicted molecular weight: 42 kDa. |
Target
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Function
Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus. -
Sequence similarities
Belongs to the RSAD2 family. -
Cellular localization
Endoplasmic reticulum membrane. Golgi apparatus. Probably associates with the cytosolic side of the endoplasmic reticulum. Infection with human cytomegalovirus (HCMV) causes relocation to the Golgi apparatus and to cytoplasmic vacuoles which also contain HCMV proteins glycoprotein B and pp28. - Information by UniProt
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Database links
- Entrez Gene: 506415 Cow
- Entrez Gene: 91543 Human
- Entrez Gene: 58185 Mouse
- Entrez Gene: 100190846 Orangutan
- Entrez Gene: 65190 Rat
- Omim: 607810 Human
- SwissProt: Q2HJF9 Cow
- SwissProt: Q8WXG1 Human
see all -
Alternative names
- 2510004L01Rik antibody
- cig 33 antibody
- CIG 5 antibody
see all
Datasheets and documents
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Datasheet download
References (0)
ab208286 has not yet been referenced specifically in any publications.