Key features and details
- Rabbit polyclonal to Viperin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Viperin antibody
See all Viperin primary antibodies
DescriptionRabbit polyclonal to Viperin
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Orangutan
Recombinant fragment corresponding to Human Viperin aa 42-361.
LATKRRKQQLVLRGPDETKEEEEDPPLPTTPTSVNYHFTRQCNYKCGFCF HTAKTSFVLPLEEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVR FCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISCDSFDEEVNVLI GRGQGKKNHVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKALN PVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFLERHKEVSCLVP ESNQKMKDSYLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEK MFLKRGGKYIWSKADLKLDW
Database link: Q8WXG1
- IHC-P: Human skin and kidney tissues.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab235895 in the following tested applications.
|IHC-P||1/20 - 1/200.|
FunctionInvolved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.
Sequence similaritiesBelongs to the RSAD2 family.
Cellular localizationEndoplasmic reticulum membrane. Golgi apparatus. Probably associates with the cytosolic side of the endoplasmic reticulum. Infection with human cytomegalovirus (HCMV) causes relocation to the Golgi apparatus and to cytoplasmic vacuoles which also contain HCMV proteins glycoprotein B and pp28.
- Information by UniProt
- 2510004L01Rik antibody
- cig 33 antibody
- CIG 5 antibody
ab235895 has not yet been referenced specifically in any publications.