Overview

  • Product name

    Anti-Viperin antibody [MaP.VIP]
    See all Viperin primary antibodies
  • Description

    Mouse monoclonal [MaP.VIP] to Viperin
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, Flow Cyt, ICC/IF, IPmore details
    Unsuitable for: IHC-Fr
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Recombinant fragment corresponding to amino acids 92-362 of Mouse Viperin

Properties

Applications

Our Abpromise guarantee covers the use of ab107359 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 42 kDa. The typical starting working dilution is 1:50.
Flow Cyt Use at an assay dependent concentration.

The typical starting working dilution is 1:50.

 

 

 

ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

 

ICC/IF Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for IHC-Fr.
  • Target

    • Function

      Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.
    • Sequence similarities

      Belongs to the RSAD2 family.
    • Cellular localization

      Endoplasmic reticulum membrane. Golgi apparatus. Probably associates with the cytosolic side of the endoplasmic reticulum. Infection with human cytomegalovirus (HCMV) causes relocation to the Golgi apparatus and to cytoplasmic vacuoles which also contain HCMV proteins glycoprotein B and pp28.
    • Information by UniProt
    • Database links

    • Alternative names

      • 2510004L01Rik antibody
      • cig 33 antibody
      • CIG 5 antibody
      • cig-33 antibody
      • CIG-5 antibody
      • CIG33 antibody
      • CIG5 antibody
      • Cytomegalovirus induced gene 5 protein antibody
      • Cytomegalovirus-induced gene 5 protein antibody
      • endoplasmic reticulum-associated antibody
      • interferon-inducible antibody
      • Radical S adenosyl methionine domain containing 2 antibody
      • Radical S-adenosyl methionine domain-containing protein 2 antibody
      • RSAD 2 antibody
      • Rsad2 antibody
      • RSAD2_HUMAN antibody
      • RSDA-2 antibody
      • VIG 1 antibody
      • vig1 antibody
      • Viperin antibody
      • Virus inhibitory protein antibody
      • virus inhibitory protein endoplasmic reticulum associated interferon inducible antibody
      see all

    References

    This product has been referenced in:

    • Lindqvist R  et al. Cell-type- and region-specific restriction of neurotropic flavivirus infection by viperin. J Neuroinflammation 15:80 (2018). WB ; Mouse . Read more (PubMed: 29544502) »
    • Upadhyay AS  et al. Cellular requirements for iron-sulfur cluster insertion into the antiviral radical SAM protein viperin. J Biol Chem 292:13879-13889 (2017). Read more (PubMed: 28615450) »
    See all 4 Publications for this product

    Customer reviews and Q&As

    1-2 of 2 Abreviews or Q&A

    Answer

    Voici le lien vers la publication où l'anticorps anti-Viperin antibody [MaP.VIP] a été utilisé :http://www.jimmunol.org/content/184/10/5723.full.pdf

    J'espère que ces informations vous seront utiles. N'hésitez pas à nous contacter de nouveau si vous avez d'autres questions.

    Read More

    Answer

    Merci de nous avoir contactés.

    Je suis donc en contact avec la source de l'anticorps ab107359 afin de connaitre le protocole Cytométrie en Flux utilisé avec cet anticorps.

    Je me permets de vous informer à nouveau que nos produits sont garantis pour fonctionner tels qu'ils sont décrits sur la fiche technique (si le problème nous est communiqué dans les 6 mois qui suivent la commande) et que nous pouvons donc toujours résoudre le problème que vous avez rencontré en vous remboursant, vous faire un avoir, ou vous envoyer un anticorps de remplacement.

    En échange, nous serions ravis si vous pouviez nous communiquer quelques détails concernant votre protocole en remplissant le questionnaire ci-joint. Ces informations sont très importantes pour nous car elles nous permettent d'investiguer la source du problème rencontré avec cet anticorps et de prendre les dispositions nécessaires pour assurer une bonne qualité de nos produits.

    Read More

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