Anti-Visfatin antibody (ab24149)
Key features and details
- Rabbit polyclonal to Visfatin
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Visfatin antibody
See all Visfatin primary antibodies -
Description
Rabbit polyclonal to Visfatin -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Synthetic peptide:
SFDEIRKNAQ LNIELEAAHH
, corresponding to C terminal amino acids 472-491 of Human PBEF. -
Positive control
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab24149 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| WB |
Human
|
| All applications |
Pig
|
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500. Detects a band of approximately 52 kDa.
|
| Notes |
|---|
|
WB
1/500. Detects a band of approximately 52 kDa. |
Target
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Function
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. -
Tissue specificity
Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues. -
Pathway
Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1. -
Sequence similarities
Belongs to the NAPRTase family. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 10135 Human
- Omim: 608764 Human
- SwissProt: P43490 Human
- SwissProt: Q52I78 Pig
- Unigene: 489615 Human
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Alternative names
- 1110035O14Rik antibody
- AI314458 antibody
- AI480535 antibody
see all
Images
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Western blot - Anti-Visfatin antibody (ab24149)Anti-Visfatin antibody (ab24149) + Human adipose tissue lysate
Observed band size: 52 kDa why is the actual band size different from the predicted?
Datasheets and documents
References (4)
ab24149 has been referenced in 4 publications.
- Oppenheimer H et al. Set7/9 impacts COL2A1 expression through binding and repression of SirT1 histone deacetylation. J Bone Miner Res 29:348-60 (2014). PubMed: 23873758
- Naesens L et al. Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir). Mol Pharmacol 84:615-29 (2013). PubMed: 23907213
- Mayi TH et al. Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages. FEBS J 277:3308-20 (2010). WB ; Human . PubMed: 20608974
- Tan BK et al. In vivo and ex vivo regulation of visfatin production by leptin in human and murine adipose tissue: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways. Endocrinology 150:3530-9 (2009). WB ; Human, Mouse . PubMed: 19389835
